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Endocannabinoid system

Researchers conducting studies on the effects of cannabis on the human body probably did not expect the scale of discovery that has been made in this way. The research confirmed the presence of the endocannabinoid system in our body, which is activated under the influence of cannabinoids produced by our body and those supplied from the outside (mainly from cannabis). Find out what a cannabinoid system is, get to know it and read what effect its discovery has on our health.

What is the endocannabinoid system?

At the very beginning of the discussion on the cannabinoid system, it should be noted that science still did not discover all its properties. Intensive research has, however, established some undeniable facts about the effects of cannabinoids on the human body. It is undeniable that there are cannabinoid receptors in the human body and that our body produces specific molecules that stimulate the previously mentioned receptors for specific reactions. These reactions can be known to us, such as:

  • Ache
  • Hunger
  • feeling of satiety
  • mood swings
  • relaxation
  • dream

Researchers have proven that the endocannabinoid system has stimulating and regulating properties for individual processes and activities in our body.


Endogenous and exogenous cannabinoids


As the name suggests, the endocannabinoid system is an internal system, although cell receptors can also be stimulated by substances supplied from the outside, called exocannabinoids. The most well-known source of occurrence of exocannabinoids is cannabis, in particular tetrahydrocannabinol (THC) and cannabidiol (CBD).

At the other end we have endogenous cannabinoids, that is, those that our body produces on its own. The most important substances examined and identified today include, among others: anandamide, found in many parts of the human body excluding the brain, and 2-AG, whose largest amounts are located in the cerebral area. Endocannabinoids are nothing but neurotransmitters, performing an indispensable function for the proper functioning of our body, which can lead to the development of dangerous diseases.

CB1 and CB2 receptors 

As mentioned earlier, endogenous and exogenous cannabinoids stimulate cellular receptors found in our body. These receptors are divided into two basic groups: CB1 and CB2. CB1 receptors are located on various parts of our body, including near the spine and in the cerebral area. It is them that largely determine the pain and intensity of pain, due to the fact that they are also in the nerve endings, through which we “feel” pain. In turn, CB2 receptors are found mainly in the immune system and in other areas of our body.

Endocannabinoid system and our health

In addition to the basic functions of the cannabinoid system, such as the regulation of basic life activities at the forefront of metabolism, sleep or pain, this system also affects many other processes, ranging from stimulating our memory, through control of digestion, to appetite and fertility. Ongoing research also concerns the impact of exogenous cannabinoids, in particular the impact of THC on our body. It is known that THC affects our psyche, but at this point the game is about something else – it examines the possible impact of THC on pain relief, treatment of asthma and even cancer.

Despite many unknowns, one thing is certain – the endocannabinoid system in our body does not only exist, but also has an extremely important function. So you can be sure that we will hear the effects of research of scientists who inform the world every now and then about newly discovered types of cannabinoids and their impact on particular processes in our body.